Fig. 1 · Structure
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Calceolarioside B
Phenylethanoid Glycoside
Calceolarioside B is a phenylethanoid glycoside that exhibits significant inhibitory activity against Rho-like GTPase RalA (RLAR) with an IC50 value of 23.99 μM. This compound has demonstrated the ability to impede the entry of the Omicron BA.2 variant into host cells, while also reducing interleukin-6 (IL-6) levels, indicating its potential for immunomodulation. Additionally, Calceolarioside B exhibits anticancer properties, particularly against hormone-independent prostate cancer, making it a valuable reagent for research in cancer therapy and immune response modulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 105471-98-5 |
| Applications | Phenylethanoid Glycoside |
| Formula | C23H26O11 |
| Molecular Weight | 478.45 |
| SMILES | O[C@H]([C@@H](O)[C@@H]1O)[C@@H](O[C@@H]1COC(/C=C/C2=CC(O)=C(O)C=C2)=O)OCCC3=CC(O)=C(O)C=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.