Fig. 1 · Structure
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Calcium 2-hydroxypropanoate pentahydrate
HCAR1 Activator
Calcium 2-hydroxypropanoate pentahydrate is a potent activator of hydroxycarboxylic acid receptor 1 (HCAR1) and serves as an epigenetic modulator by facilitating the lactylation of lysine residues. As a glycolysis end-product, it connects glycolytic activity with oxidative phosphorylation processes. This compound is identified as an oncometabolite and plays a protective role in the immune response, particularly in enhancing anti-tumor immunity. It is valuable for research applications focused on metabolism, cancer biology, and immunology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 5743-47-5 |
| Applications | HCAR1 Activator |
| Formula | C3H6O3.0.5Ca.2.5H2O |
| Molecular Weight | 155.17 |
| SMILES | O=C(C(C)O)O.[Ca].O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.