Fig. 1 · Structure
Documents & Downloads
Calcium dextrofolinate
Calcium folinate Stereoisomer
Calcium dextrofolinate is a stereoisomer of Calcium folinate, functioning primarily as a rescue agent for mitigating methotrexate-induced toxicity. This biological folic acid derivative promotes rapid cellular recovery by enhancing nucleotide synthesis and counteracting the effects of antifolate therapies. It is commonly used in clinical settings to protect healthy tissues during cancer treatment, making it a valuable reagent for research in cancer pharmacology and toxicology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 115940-48-2 |
| Applications | Calcium folinate Stereoisomer |
| Formula | C20H21CaN7O7 |
| Molecular Weight | 511.50 |
| Synonyms | (6R)-Leucovorin calcium; (6R)-Folinic acid calcium |
| SMILES | O=C([O-])CC[C@@H](C([O-])=O)NC(C1=CC=C(NC[C@H]2N(C=O)C3=C(N=C(N)NC3=O)NC2)C=C1)=O.[Ca+2] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.