Camptothecin

Catalog No.: A10174

Topoisomerase I inhibitor

Camptothecin Chemical Structure

CAS NO. CAS:7689-03-4

Camptothecin is a cytotoxic quinoline alkaloid which inhibits the DNA enzyme topoisomerase I (topo I).

Availability: In stock

Package Price Qty
100 mg
$40.00
200 mg
$70.00
500 mg
$140.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Camptothecin is a cytotoxic quinoline alkaloid which inhibits the DNA enzyme topoisomerase I (topo I).
Targets
Topo I (Cell-free assay)
0.68 μM
In vitro (25°C) DMSO 3 mg/mL (8.61 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.7 mL 143.51 mL 287.03 mL
0.5 mM 5.74 mL 28.7 mL 57.41 mL
1 mM 2.87 mL 14.35 mL 28.7 mL
5 mM 0.57 mL 2.87 mL 5.74 mL

*The above data is based on the productmolecular weight 348.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10174
Actions Inhibitor
M. Wt 348.4
Formula C20H16N2O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. CAS:7689-03-4
Synonyms N/A
SMILES CC[[email protected]@]1(C2=C(COC1=O)C(=O)N3CC4=CC5=CC=CC=C5N=C4C3=C2)O

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