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Form	MW
Canfosfamide This page	787.47
Canfosfamide hydrochloride	823.94

Canfosfamide

Anticancer Agent

Canfosfamide is a glutathione analogue prodrug that acts primarily as an anticancer agent through activation by glutathione S-transferase P1-1, leading to apoptosis in target cells. Additionally, it inhibits the catalytic activity of DNA-dependent protein kinase (DNA-PK), contributing to its therapeutic effects. This compound serves as a valuable tool for researchers investigating mechanisms of malignancy and developing targeted cancer therapies.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	158382-37-7
Applications	Anticancer Agent
Formula	C₂₆H₄₀Cl₄N₅O₁₀PS
Molecular Weight	787.47
Synonyms	TLK-286; TER286
SMILES	ClCCN(CCCl)P(N(CCCl)CCCl)(OCCS(C[C@H](NC(CC[C@H](N)C(O)=O)=O)C(N[C@H](C1=CC=CC=C1)C(O)=O)=O)(=O)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.