Fig. 1 · Structure
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Canrenoate potassium
Mineralocorticoid Receptor Antagonist
Canrenoate potassium is a competitive antagonist of the mineralocorticoid receptor, primarily through its active metabolite canrenone. This compound exhibits significant diuretic activity and is employed in research related to hypertension and fluid balance disorders. Its mechanism involves the inhibition of aldosterone's effects, making it relevant for studies on cardiovascular physiology and pathologies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 2181-04-6 |
| Applications | Mineralocorticoid Receptor Antagonist |
| Formula | C22H29KO4 |
| Molecular Weight | 396.56 |
| Synonyms | Aldadiene potassium; SC-14266 |
| SMILES | C[C@@]12[C@@](CCC(O[K])=O)(O)CC[C@@]1([H])[C@]3([H])C=CC4=CC(CC[C@]4(C)[C@@]3([H])CC2)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.