Fig. 1 · Structure
Documents & Downloads
Cantharidic acid disodium
PP2A/PP1 Inhibitor
Cantharidic acid disodium is a selective inhibitor of protein phosphatase 2A (PP2A) and protein phosphatase 1 (PP1), with reported IC50 values of 50 nM and 600 nM, respectively. This compound is derived from the hydrolysis of Cantharidin, known for inducing apoptosis in various human cancer cell lines. Its specific inhibitory action on PP2A and PP1 makes it a valuable tool for research into cancer biology and phosphatase-mediated signaling pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1465-77-6 |
| Applications | PP2A/PP1 Inhibitor |
| Formula | C10H12Na2O5 |
| Molecular Weight | 258.18 |
| SMILES | O=C([C@@]([C@@]1(C)C(O[Na])=O)([C@@H]2O[C@H]1CC2)C)O[Na] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.