Fig. 1 · Structure
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Cantuzumab ravtansine
CanAg ADC
Cantuzumab ravtansine is an antibody-drug conjugate (ADC) consisting of the humanized monoclonal antibody huC242 covalently linked to the cytotoxic agent DM4. This compound exhibits significant antitumor activity against various CanAg-positive human tumor xenografts. It is utilized in research focused on targeted cancer therapies and the exploration of ADC mechanisms in tumor cell modulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 868747-45-9 |
| Applications | CanAg ADC |
| Molecular Weight | 150000 (average) |
| Synonyms | IMGN242; huC242-DM4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.