Fig. 1 · Structure
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Captopril hydrochloride
ACE Inhibitor
Captopril hydrochloride is a thiol-containing competitive angiotensin-converting enzyme (ACE) inhibitor, recognized for its antihypertensive properties, with an IC50 of 0.025 μM. This compound is commonly utilized in research focused on hypertension and congestive heart failure. Additionally, Captopril hydrochloride serves as an inhibitor of New Delhi metallo-β-lactamase-1 (NDM-1) with an IC50 value of 7.9 μM, making it valuable in studies related to antibiotic resistance.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 198342-23-3 |
| Applications | ACE Inhibitor |
| Formula | C9H16ClNO3S |
| Molecular Weight | 253.75 |
| Synonyms | SQ 14225 hydrochloride |
| SMILES | O=C(O)[C@H]1N(C([C@H](C)CS)=O)CCC1.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.