Carazolol-d7 hydrochloride

Catalog No.: A58360
Stable Isotope
Carazolol-d7 hydrochloride is a deuterium-labeled derivative of Carazolol hydrochloride, primarily targeting β1 and β2 adrenoceptors as a potent antagonist. Additionally, it acts as a selective agonist for the β3-adrenoceptor, making it a versatile tool in cardiovascular research. This reagent is valuable for studying mechanisms in hypertension and related conditions, allowing for enhanced clarity in the investigation of adrenergic signaling pathways.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCarazolol-d7 hydrochloride is a deuterium-labeled derivative of Carazolol hydrochloride, primarily targeting β1 and β2 adrenoceptors as a potent antagonist. Additionally, it acts as a selective agonist for the β3-adrenoceptor, making it a versatile tool in cardiovascular research. This reagent is valuable for studying mechanisms in hypertension and related conditions, allowing for enhanced clarity in the investigation of adrenergic signaling pathways.
Product Information
Catalog NumA58360
FormulaC18H16D7ClN2O2
Molecular Weight341.88
CAS Number1276197-44-4
SMILES[2H]C([2H])([2H])C(C([2H])([2H])[2H])([2H])NCC(O)COC1=C2C3=CC=CC=C3NC2=CC=C1.Cl
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