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Carbiphene

Catalog No.: A66935
GABAA receptor Positive Allosteric Modulator
Carbiphene is a positive allosteric modulator of the GABAA receptor. It inhibits [35S] TBPS binding while enhancing [3H] muscimol binding in rat forebrain membranes, targeting specific subsets of the GABAA receptor. This compound is valuable in research focused on schizophrenia and related neurological disorders.
Carbiphene 15687-16-8 GABAA receptor Positive Allosteric Modulator
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCarbiphene is a positive allosteric modulator of the GABAA receptor. It inhibits [35S] TBPS binding while enhancing [3H] muscimol binding in rat forebrain membranes, targeting specific subsets of the GABAA receptor. This compound is valuable in research focused on schizophrenia and related neurological disorders.
Product Information
Catalog NumA66935
FormulaC28H34N2O2
Molecular Weight430.59
CAS Number15687-16-8
SMILESO=C(N(C)CCN(C)CCC=1C=CC=CC1)C(OCC)(C=2C=CC=CC2)C=3C=CC=CC3
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Neuronal Signaling > GABA Receptors