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Carbonic anhydrase activator 1

CA Inhibitor

Carbonic Anhydrase Activator 1 is a potent activator of carbonic anhydrase (CA) enzymes, selectively targeting human CA I, CA VA, and CA VII with KAs of 7.8, 3.9, and 2.1 μM, respectively. This compound is orally bioavailable and effectively crosses the blood-brain barrier, making it a valuable tool in studies of diseases such as cancer, glaucoma, cardiovascular disorders, and neurodegenerative conditions like epilepsy. Its pharmacological properties support its application in investigating therapeutic strategies and mechanisms related to these pathological states.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Activator
CAS Number	2374923-30-3
Applications	CA Inhibitor
Formula	C₁₇H₁₁N₅OS
Molecular Weight	333.37
SMILES	N#CC1=C(C2=CC=CO2)C(C#N)=C(N)N=C1SCC3=CC=NC=C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.