Carbonic anhydrase inhibitor 19 is a potent inhibitor of the carbonic anhydrase isoforms hCA II and hCA XII, demonstrating inhibitory constants (Kis) of 9.4 nM and 6.7 nM, respectively. This compound exhibits significant biological activity by effectively lowering intraocular pressure (IOP), making it a valuable tool for research in glaucoma treatment and related ocular conditions. Its selective inhibition profile allows for the exploration of therapeutic strategies targeting carbonic anhydrases in various biological contexts.
Carbonic anhydrase inhibitor 19 is a potent inhibitor of the carbonic anhydrase isoforms hCA II and hCA XII, demonstrating inhibitory constants (Kis) of 9.4 nM and 6.7 nM, respectively. This compound exhibits significant biological activity by effectively lowering intraocular pressure (IOP), making it a valuable tool for research in glaucoma treatment and related ocular conditions. Its selective inhibition profile allows for the exploration of therapeutic strategies targeting carbonic anhydrases in various biological contexts.
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