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Carbonic anhydrase inhibitor 19

Carbonic anhydrase inhibitor

Carbonic anhydrase inhibitor 19 is a potent inhibitor of the carbonic anhydrase isoforms hCA II and hCA XII, demonstrating inhibitory constants (Kis) of 9.4 nM and 6.7 nM, respectively. This compound exhibits significant biological activity by effectively lowering intraocular pressure (IOP), making it a valuable tool for research in glaucoma treatment and related ocular conditions. Its selective inhibition profile allows for the exploration of therapeutic strategies targeting carbonic anhydrases in various biological contexts.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3033374-40-9
Applications	Carbonic anhydrase inhibitor
Formula	C₂₃H₂₅N₃O₆S₂
Molecular Weight	503.59
SMILES	OC(CNC1=CC(CN(S(C2=CC=CC=C2)(=O)=O)CCC3=CC=C(S(N)(=O)=O)C=C3)=CC=C1)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.