Fig. 1 · Structure
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Carbonic anhydrase inhibitor 22
Carbonic Anhydrase Inhibitor
Carbonic Anhydrase Inhibitor 22 is a sulfonamide compound that selectively inhibits carbonic anhydrases, with Ki values of 762 nM for hCA I, 20.3 nM for hCA II, 8.3 nM for hCA VII, 17.9 nM for hCA IX, and 10.5 nM for hCA XII. This compound's potent inhibition of multiple isoforms of carbonic anhydrase makes it valuable for studying biochemical pathways involving pH regulation and ion transport. It serves as a useful tool in research related to metabolic disorders, cancer, and other conditions where carbonic anhydrases play a critical role.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 146533-50-8 |
| Applications | Carbonic Anhydrase Inhibitor |
| Formula | C13H13NO3S |
| Molecular Weight | 263.31 |
| SMILES | O=S(C1=CC=C(OCC2=CC=CC=C2)C=C1)(N)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.