Fig. 1 · Structure
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Carbonic anhydrase inhibitor 6
Carbonic Anhydrase Inhibitor
Carbonic anhydrase inhibitor 6 is a potent inhibitor of human carbonic anhydrases (hCAs), exhibiting Ki values of 9.7 nM for hCA IX, 35.2 nM for hCA II, 88.5 nM for hCA XII, and 91.8 nM for hCA I. This compound is valuable for research applications targeting hCA-related pathways in cancer, glaucoma, and other diseases where carbonic anhydrases play a crucial role in regulating pH and fluid balance. Its high specificity and potency make it an essential tool for biochemical investigations and drug development efforts focusing on hCA modulation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1013213-84-7 |
| Applications | Carbonic Anhydrase Inhibitor |
| Formula | C26H25N3O5S |
| Molecular Weight | 491.56 |
| SMILES | O=C(C1=CC(C2=CC=C(OC)C(OC)=C2)=NC3=CC=CC=C13)NCCC4=CC=C(S(=O)(N)=O)C=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.