Fig. 1 · Structure
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Carbonic anhydrase inhibitor 7
Carbonic Anhydrase Inhibitor
Carbonic Anhydrase Inhibitor 7 is a highly effective inhibitor of human carbonic anhydrase enzymes, with inhibition constants (Kis) of 6.5 nM for hCA IX, 7.1 nM for hCA II, 72.1 nM for hCA XII, and 255.8 nM for hCA I. This compound exhibits potent biological activity, making it a valuable tool for investigating the role of carbonic anhydrases in various physiological and pathological processes. It is particularly useful in cancer research and related fields where hCA IX is implicated.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 546105-61-7 |
| Applications | Carbonic Anhydrase Inhibitor |
| Formula | C23H17N3O5S |
| Molecular Weight | 447.46 |
| SMILES | O=C(C1=CC(C2=CC=C(OCO3)C3=C2)=NC4=CC=CC=C14)NC5=CC=C(S(=O)(N)=O)C=C5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.