Fig. 1 · Structure
Documents & Downloads
Carboxyatractyloside dipotassium
ADP/ATP Carrier Inhibitor
Carboxyatractyloside dipotassium is a potent inhibitor of the ADP/ATP carrier located in the inner mitochondrial membrane. Its primary mechanism involves the inhibition of mitochondrial ADP/ATP transport, leading to increased production of reactive oxygen species (ROS) and subsequent calcium release, resulting in mitochondrial dysfunction. This compound is valuable for research into mitochondrial bioenergetics, oxidative stress, and related pathophysiological conditions, including neurodegeneration, as evidenced by its ability to induce lethargy, weakness, and seizures in animal models.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 33286-30-5 |
| Applications | ADP/ATP Carrier Inhibitor |
| Formula | C31H44K2O18S2 |
| Molecular Weight | 847.00 |
| Synonyms | Gummiferin dipotassium |
| SMILES | C=C([C@H](CC1)C2)[C@H](O)[C@@]32CC[C@]4([H])C(C(O)=O)(C(O)=O)C[C@@H](O[C@H]5[C@@H]([C@H]([C@@H]([C@@H](CO)O5)OS(=O)(O[K])=O)OS(=O)(O[K])=O)OC(CC(C)C)=O)C[C@@]4(C)[C@@]31[H] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.