Fig. 1 · Structure
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Carboxyatractyloside tripotassium
ADP/ATP Carrier Inhibitor
Carboxyatractyloside tripotassium is a diterpenoid that functions as an inhibitor of the ADP/ATP carrier in mitochondria. By inhibiting mitochondrial ADP/ATP transport, it promotes reactive oxygen species (ROS) production and induces calcium release, leading to mitochondrial dysfunction. This compound has been shown to induce symptoms such as lethargy, weakness, and epileptic seizures in animal models, making it a valuable tool for studying mitochondrial biology and related disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 77228-71-8 |
| Applications | ADP/ATP Carrier Inhibitor |
| Formula | C31H43K3O18S2 |
| Molecular Weight | 885.09 |
| Synonyms | Gummiferin tripotassium |
| SMILES | C=C([C@H](CC1)C2)[C@H](O)[C@@]32CC[C@]4([H])[C@@](C(O)=O)(C(O[K])=O)C[C@@H](O[C@@H]5[C@H]([C@@H]([C@H]([C@H](CO)O5)OS(=O)(O[K])=O)OS(=O)(O[K])=O)OC(CC(C)C)=O)C[C@@]4(C)[C@@]31[H] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.