Fig. 1 · Structure
Documents & Downloads
Carebastine-d5 Methyl Ester
Stable Isotope
Carebastine-d5 Methyl Ester is a deuterium-labeled derivative of Carebastine, the active metabolite of Ebastine and a potent histamine H1 receptor antagonist. This compound exhibits significant biological activity by inhibiting VEGF-induced proliferation, migration, and angiogenesis in human umbilical vein endothelial cells (HUVEC) and human pulmonary artery endothelial cells (HPAEC) in a dose-dependent manner. It also demonstrates the ability to suppress the expression of macrophage migration inhibitory factor, making it a valuable tool for research in inflammation and angiogenesis.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1190019-51-2 |
| Applications | Stable Isotope |
| Formula | C33H34D5NO4 |
| Molecular Weight | 518.70 |
| SMILES | O=C(C1=CC=C(C=C1)C(C)(C)C(OC)=O)CCCN(CC2)CCC2OC(C3=CC=CC=C3)C4=C([2H])C([2H])=C([2H])C([2H])=C4[2H] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.