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Carebastine-d5

Stable Isotope

Carebastine-d5 is the deuterium-labeled derivative of Carebastine, a potent histamine H1 receptor antagonist. This stable isotope is utilized in research to explore the pharmacokinetics and metabolic pathways of Carebastine and its effects on various biological systems. Carebastine demonstrates significant inhibition of VEGF-induced proliferation, migration, and angiogenesis in human umbilical vein endothelial cells (HUVEC) and human pulmonary artery endothelial cells (HPAEC), while also suppressing the expression of macrophage migration inhibitory factor.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1189661-02-6
Applications	Stable Isotope
Formula	C₃₂H₃₂D₅NO₄
Molecular Weight	504.67
SMILES	O=C(C1=CC=C(C=C1)C(C)(C)C(O)=O)CCCN(CC2)CCC2OC(C3=CC=CC=C3)C4=C([2H])C([2H])=C([2H])C([2H])=C4[2H]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.