Fig. 1 · Structure
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Cariprazine-d8
Antipsychotic Agent
Cariprazine-d8 is a deuterium-labeled variant of Cariprazine, acting primarily as an antipsychotic agent. This compound demonstrates a high affinity for dopamine D3 receptors (Ki = 0.085 nM) and D2 receptors (Ki = 0.49 nM), along with a moderate affinity for the 5-HT1A receptor (Ki = 2.6 nM). Cariprazine-d8 is useful for investigating the pharmacodynamics of antipsychotics and studying receptor binding characteristics in neuropharmacological research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1308278-50-3 |
| Applications | Antipsychotic Agent |
| Formula | C21H24D8Cl2N4O |
| Molecular Weight | 435.46 |
| Synonyms | RGH-188 d8 |
| SMILES | ClC1=C(C=CC=C1Cl)N2C([2H])([2H])C([2H])([2H])N(C([2H])([2H])C2([2H])[2H])CC[C@@H]3CC[C@H](CC3)NC(N(C)C)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.