Fig. 1 · Structure
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Carprofen-d3
Stable Isotope
Carprofen-d3 is a deuterium-labeled derivative of Carprofen, a non-steroidal anti-inflammatory drug known for its multi-target inhibition of fatty acid amide hydrolase (FAAH) and cyclooxygenases (COX). It exhibits inhibitory concentrations (IC50) of 3.9 μM for COX-2, 22.3 μM for COX-1, and 78.6 μM for FAAH. This stable isotope is useful in pharmacokinetic studies, facilitating the investigation of drug metabolism and distribution in biological systems.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1173019-42-5 |
| Applications | Stable Isotope |
| Formula | C15H9D3ClNO2 |
| Molecular Weight | 276.73 |
| SMILES | ClC1=CC=C2NC3=CC(C(C([2H])([2H])[2H])C(O)=O)=CC=C3C2=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.