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Casirivimab
Casirivimab (REGN10933) is a human monoclonal antibody designed to specifically target the SARS-CoV-2 virus, responsible for COVID-19. This antibody has shown limitations in its efficacy against emerging COVID-19 variants. For enhanced therapeutic potential, Casirivimab can be administered in conjunction with Imdevimab. This combination has been demonstrated to modify the pulmonary response in K18-hACE2 transgenic mice infected with the SARS-CoV-2 δ variant, leading to a significant reduction in viral load and amelioration of clinical symptoms.
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Biological Activity
Product Details
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2415933-42-3 |
| Synonyms | REGN10933 |
Storage
Store lyophilized at -20°C, keep desiccated.
In lyophilized form, the antibody is stable for 36 months.
After reconstitution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.