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CAST-calpain-2 stabilizer-1

Protein Stabilizer

CAST-calpain-2 stabilizer-1 is a potent stabilizer of the CAST-calpain-2 interaction, designed for effective blood-brain barrier penetration. This compound selectively enhances the stability of calpain-2 without exhibiting activity against GSK3. It serves as a valuable tool in the research of Huntington's disease and tauopathies, facilitating studies into neurodegenerative mechanisms and potential therapeutic interventions.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Stabilizer
CAS Number	3110929-05-7
Applications	Protein Stabilizer
Formula	C₂₂H₂₀Cl₂N₆O₂
Molecular Weight	471.34
SMILES	N#CC1=CN=C(C=C1)OCCNC2=NC=C(N3CCOCC3)C(C4=C(Cl)C=C(Cl)C=C4)=N2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.