CAY10614 is a potent TLR4 antagonist that inhibits lipid A-induced activation of the TLR4 receptor, exhibiting an IC50 of 1.675 μM. This compound has demonstrated the ability to improve survival rates in mouse models of lethal endotoxin shock. CAY10614 is valuable for research applications investigating TLR4-mediated inflammatory responses and the development of therapeutic strategies targeting sepsis and other endotoxin-related conditions.
CAY10614 is a potent TLR4 antagonist that inhibits lipid A-induced activation of the TLR4 receptor, exhibiting an IC50 of 1.675 μM. This compound has demonstrated the ability to improve survival rates in mouse models of lethal endotoxin shock. CAY10614 is valuable for research applications investigating TLR4-mediated inflammatory responses and the development of therapeutic strategies targeting sepsis and other endotoxin-related conditions.
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