Fig. 1 · Structure
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CAY10781
NRP-1 and VEGF-A Interaction Inhibitor
CAY10781 is an inhibitor of the neuropilin-1 (NRP-1) and VEGF-A interaction. This compound effectively blocks VEGF-A-induced phosphorylation of VEGFR2 in Catecholamine A-differentiated (CAD) cells. CAY10781 is utilized in research focused on angiogenesis, cancer biology, and vascular signaling pathways, providing insights into the therapeutic targeting of NRP-1 and VEGF-A.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1210360-87-4 |
| Applications | NRP-1 and VEGF-A Interaction Inhibitor |
| Formula | C11H9N3O3 |
| Molecular Weight | 231.21 |
| SMILES | O=C(O)CC1=CN=C(C2=CC=CN=C2)NC1=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.