Fig. 1 · Structure
Documents & Downloads
Caylin-2
Nutlin-3 analog
Caylin-2 is a Nutlin-3 analog that functions as an inhibitor of the MDM2 protein. This compound demonstrates the ability to bind to Bcl-XL, which may influence apoptotic pathways. Caylin-2 is utilized in research focused on cancer biology, particularly in studies assessing MDM2's role in tumor suppression and cell survival mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1392830-09-9 |
| Applications | Nutlin-3 analog |
| Formula | C32H30F6N4O4 |
| Molecular Weight | 648.60 |
| SMILES | O=C(N1CC(NCC1)=O)N2[C@@H](C3=CC=C(C=C3)C(F)(F)F)[C@@H](C4=CC=C(C=C4)C(F)(F)F)N=C2C5=C(C=C(C=C5)OC)OC(C)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.