Fig. 1 · Structure
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CBiPES
mGlu2 Receptor PAM
CBiPES is a potent positive allosteric modulator of the mGlu2 receptor, exhibiting an EC50 of 92.8 nM. This compound effectively attenuates stress-induced hyperthermia and phencyclidine-induced hyperlocomotor activity, making it a valuable tool in the study of neurological disorders. CBiPES is particularly relevant for research related to Parkinson's disease and other neuropsychiatric conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 353235-01-5 |
| Applications | mGlu2 Receptor PAM |
| Formula | C21H19N3O2S |
| Molecular Weight | 377.46 |
| SMILES | CCS(N(C1=CC(C2=CC=C(C#N)C=C2)=CC=C1)CC3=CN=CC=C3)(=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.