Fig. 1 · Structure

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CBP/p300 ligand-Linker Conjugate 3

Target Protein Ligand-Linker Conjugate

CBP/p300 Ligand-Linker Conjugate 3 is designed to target the CBP/p300 complex, utilizing a specific ligand and a PROTAC linker to recruit E3 ligases. This conjugate is a valuable tool in the synthesis of PROTAC CBP/p300 Degrader-2, facilitating the targeted degradation of proteins associated with oncogenic processes. Its applications extend to cancer research, particularly in studies aimed at modulating transcriptional regulation and therapeutic interventions in related pathways.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 3102127-04-5
Applications Target Protein Ligand-Linker Conjugate
Formula C34H39F2N5O2
Molecular Weight 587.70
SMILES
CC(C(N(C1=C2)C)=O)=CC1=C(N3CCCC(C=C4C5=CN(C6CCNCC6)N=C5)=C3C=C4C(F)F)C=C2C7CCOCC7

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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