Fig. 1 · Structure
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CBR-6672
Type II NADH Dehydrogenase Inhibitor
CBR-6672 is a specific inhibitor of type II NADH dehydrogenase in mycobacterium tuberculosis (Mtb). With a minimum inhibitory concentration (MIC) of 0.14 μM against Mtb, this compound demonstrates potent antibacterial activity. It serves as a valuable tool for research aimed at understanding Mtb metabolism and developing novel therapeutics for tuberculosis treatment.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2225885-40-3 |
| Applications | Type II NADH Dehydrogenase Inhibitor |
| Formula | C17H20FN3O2S |
| Molecular Weight | 349.42 |
| SMILES | O=C1N=C(NC2=C1C(F)=CC=C2)SCC(NC3CCCCCC3)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.