Cbz-B3A

Catalog No.: A16857

4EBP1 inhibitor

Cbz-B3A

Cbz-B3A Chemical Structure

CAS NO. 1884710-81-9

Cbz-B3A is a potent and selective inhibitor of mTORC1 signaling that appear to bind to ubiquilins 1, 2, and 4, and Cbz-B3A inhibits the phosphorylation of eIF4E-binding protein 1 (4EBP1).

Availability: In stock

Package Price Qty
5 mg
$200.00
10 mg
$350.00
50 mg
$1,100.00
100 mg
$1,900.00
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Biological Activity

Cbz-B3A is a potent and selective inhibitor of mTORC1 signaling that appear to bind to ubiquilins 1, 2, and 4, and Cbz-B3A inhibits the phosphorylation of eIF4E-binding protein 1 (4EBP1).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 14.15 mL 70.73 mL 141.47 mL
0.5 mM 2.83 mL 14.15 mL 28.29 mL
1 mM 1.41 mL 7.07 mL 14.15 mL
5 mM 0.28 mL 1.41 mL 2.83 mL

*The above data is based on the productmolecular weight 706.87. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16857
Actions Inhibitor
CAS No. 1884710-81-9
Formula C35H58N6O9
M. Wt 706.87
Solubility DMSO
Purity >98%
Synonyms Cbz-B3A, CbzB3A
SMILES O=C(OC(C)(C)C)N/C(NC(OC(C)(C)C)=O)=N/CCC[[email protected]](NC(OC(C)(C)C)=O)C(NCCCCCCNC(OCC1=CC=CC=C1)=O)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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