Biological Activity
Cbz-B3A is a potent and selective inhibitor of mTORC1 signaling that appear to bind to ubiquilins 1, 2, and 4, and Cbz-B3A inhibits the phosphorylation of eIF4E-binding protein 1 (4EBP1).
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 14.15 mL | 70.73 mL | 141.47 mL |
0.5 mM | 2.83 mL | 14.15 mL | 28.29 mL |
1 mM | 1.41 mL | 7.07 mL | 14.15 mL |
5 mM | 0.28 mL | 1.41 mL | 2.83 mL |
*The above data is based on the productmolecular weight 706.87. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A16857 |
---|---|
Actions | Inhibitor |
CAS No. | 1884710-81-9 |
Formula | C35H58N6O9 |
M. Wt | 706.87 |
Solubility | DMSO |
Purity | >98% |
Synonyms | Cbz-B3A, CbzB3A |
SMILES | O=C(OC(C)(C)C)N/C(NC(OC(C)(C)C)=O)=N/CCC[[email protected]](NC(OC(C)(C)C)=O)C(NCCCCCCNC(OCC1=CC=CC=C1)=O)=O |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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