CC-3060

Catalog No.: A80455
Cereblon Modulator
CC-3060 is a Cereblon modulator that facilitates the degradation of ZBTB16, showing a DC50 value of 0.47 nM in HT-1080 cells. This compound engages specific structural degrons across various zinc finger domains, effectively promoting ZBTB16's proteasomal degradation. CC-3060 has potential applications in the study of cellular processes regulated by ZBTB16 and in the development of innovative therapeutic strategies targeting this pathway.
Grouped product items
Size Price Stock Qty
1mg
$100.00
In stock
5mg
$255.00
In stock
10mg
$485.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCC-3060 is a Cereblon modulator that facilitates the degradation of ZBTB16, showing a DC50 value of 0.47 nM in HT-1080 cells. This compound engages specific structural degrons across various zinc finger domains, effectively promoting ZBTB16's proteasomal degradation. CC-3060 has potential applications in the study of cellular processes regulated by ZBTB16 and in the development of innovative therapeutic strategies targeting this pathway.
Product Information
Catalog NumA80455
FormulaC22H17N3O5
Molecular Weight403.39
CAS Number444288-86-2
SMILESO=C1NC(C(CC1)N2C(C3=C(C2=O)C(NCC4=CC5=C(C=CC=C5)O4)=CC=C3)=O)=O
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