Fig. 1 · Structure
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CC260
PI5P4Kα/PI5P4Kβ Inhibitor
CC260 is a selective inhibitor of PI5P4Kα and PI5P4Kβ, exhibiting Ki values of 40 nM and 30 nM, respectively. It demonstrates minimal to no inhibition of other kinases, including Plk1 and RSK2. This compound is valuable for studies related to cell energy metabolism, diabetes, and cancer research, providing insights into the role of these kinases in metabolic regulation and disease progression.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2411088-26-9 |
| Applications | PI5P4Kα/PI5P4Kβ Inhibitor |
| Formula | C24H29Cl2N5O2 |
| Molecular Weight | 490.43 |
| SMILES | CN(C1=O)C(C(N(C2CCCC2)[C@@H]1CC3CCCC3)=N4)=CN=C4NC5=CC(Cl)=C(C(Cl)=C5)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.