Fig. 1 · Structure
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CCW16
RNF4 Ligand
CCW16 is a ligand for RNF4, facilitating the synthesis of targeted protein degraders. It serves as a crucial cofactor in the development of PROTACs, such as CCW 28-3, by enhancing the ubiquitination process that promotes protein degradation. This reagent is essential for research involving protein homeostasis and therapeutic development using protein degradation strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Ligand / Binder |
| CAS Number | 2361138-33-0 |
| Applications | RNF4 Ligand |
| Formula | C22H20ClNO3 |
| Molecular Weight | 381.85 |
| SMILES | O=C(N(CC1=CC=CC=C1)C2=CC=C(OC3=CC=C(OC)C=C3)C=C2)CCl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.