Fig. 1 · Structure
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CCX-777
ACKR3 Agonist
CCX-777 is a partial agonist of the atypical chemokine receptor 3 (ACKR3), acting primarily through the recruitment of β-arrestin-2. This compound modulates various signaling pathways associated with chemokine receptors and is utilized in research focused on inflammation, cancer biology, and immune response. Its role in ACKR3-mediated signaling makes it a valuable tool for investigating the receptor's influence in physiological and pathological processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Partial Agonist |
| CAS Number | 1226686-36-7 |
| Applications | ACKR3 Agonist |
| Formula | C31H43N7O3S |
| Molecular Weight | 593.78 |
| SMILES | O=C(NCCN1CCCC1)CC(N2CCN(C3=C4N=CC=CC4=CC=C3OC)CCC2)C5=CSC(N6CCOCC6)=N5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.