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CDC20-IN-2

Cdc20 Inhibitor

CDC20-IN-2 is a selective inhibitor of Cdc20 with a dissociation constant (KD) of 7.65 μM. It effectively induces G2/M phase arrest and promotes the accumulation of DNA damage. By stabilizing critical substrates, including Cyclin B1 and Bim, CDC20-IN-2 enhances apoptotic signaling and inhibits tumor cell proliferation and migration, making it a valuable compound for cancer research and therapy development.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3080812-16-1
Applications	Cdc20 Inhibitor
Formula	C₂₁H₁₅Cl₄F₆N₇O₃S
Molecular Weight	701.26
SMILES	FC(F)(F)C1=CC=C(NC2=CC(Cl)=NC(NC(NC(OCCNC(C3=CN=C(C(F)(F)F)S3)=O)=O)C(Cl)(Cl)Cl)=N2)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.