Fig. 1 · Structure
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Cdc7-IN-12
CDC7 Inhibitor
Cdc7-IN-12 is a potent inhibitor of the CDC7 kinase, exhibiting an IC50 of less than 1 nM. This compound demonstrates significant antiproliferative activity in COLO205 cells, with an IC50 range of 100-1000 nM. Cdc7-IN-12 is valuable for research in cancer biology, focusing on cell cycle regulation and potential therapeutic applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2764865-33-8 |
| Applications | CDC7 Inhibitor |
| Formula | C16H14N2O2S |
| Molecular Weight | 298.36 |
| SMILES | CC1=C2CCCOC3=C(SC(C(N1)=O)=C23)C4=CC=NC=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.