Fig. 1 · Structure
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Cdc7-IN-3
CDK Inhibitor
Cdc7-IN-3 is a selective inhibitor of the Cdc7 kinase, a serine-threonine protein kinase crucial for the initiation of DNA replication during the cell cycle. This compound demonstrates potent inhibitory activity against Cdc7, making it a valuable tool for studying cell proliferation and checkpoint control mechanisms. It is suitable for research applications involving cancer biology and the exploration of therapeutic strategies that target DNA replication processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1402057-87-7 |
| Applications | CDK Inhibitor |
| Formula | C20H22N4O5 |
| Molecular Weight | 398.41 |
| SMILES | O=C(C(C/1=O)=C(NN2CCOCC2)OC1=C/C3=CNC4=NC=CC=C43)OC(C)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.