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CDK-IN-15

Catalog No.: A54371
Cyclin A Inhibitor
CDK-IN-15 is a potent inhibitor of Cyclin A, exhibiting an IC50 value of 0.14 μM. This compound is useful for studying cell cycle regulation and the inhibition of cyclin-dependent kinases in cancer research. Its biological activity makes it a valuable tool in investigating the role of Cyclin A in various cellular processes and the development of novel therapeutic strategies.
CDK-IN-15 3036232-03-5 Cyclin A Inhibitor
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionCDK-IN-15 is a potent inhibitor of Cyclin A, exhibiting an IC50 value of 0.14 μM. This compound is useful for studying cell cycle regulation and the inhibition of cyclin-dependent kinases in cancer research. Its biological activity makes it a valuable tool in investigating the role of Cyclin A in various cellular processes and the development of novel therapeutic strategies.
Product Information
Catalog NumA54371
FormulaC45H63Cl2F4N7O8
Molecular Weight976.92
CAS Number3036232-03-5
SMILESClC1=C(C[C@H](N2CCC)C(NC3(C(NCCCC[C@H](N(C)C([C@@H](NC([C@@H]4C[C@@H](F)CN4C([C@](O)(C)C(F)(F)F)=O)=O)CC5CCC5)=O)C(N[C@H](C2=O)CC(C)C)=O)=O)CC3)=O)C=C(Cl)C=C1
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Cell Cycle > CDK