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CDK1-IN-8

CDK1 Inhibitor

CDK1-IN-8 is a potent inhibitor of Cyclin-dependent kinase 1 (CDK1), primarily targeting the regulation of cell cycle progression. This compound effectively inhibits cell migration, induces apoptosis, and causes cell cycle arrest at the G2/M phase. Notably, CDK1-IN-8 leads to significant downregulation of CDK1 protein levels in HepG2 cells, making it a valuable tool for investigating mechanisms in hepatocellular carcinoma research.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3077717-99-5
Applications	CDK1 Inhibitor
Formula	C₂₈H₂₇ClFN₂O₈P
Molecular Weight	604.95
SMILES	OC1=C2C(C(C(C=C(C(NCCNC(C3=CC(F)=C(Cl)C=C3)P(OCC)(OCC)=O)=O)C=C4O)=C4C2=O)=O)=CC=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.