CDK12/13-IN-1 is a selective inhibitor of cyclin-dependent kinases 12 and 13 (CDK12/13). This compound demonstrates significant antitumor activity by interfering with the phosphorylation of RNA polymerase II, thereby disrupting transcriptional regulation in cancer cells. CDK12/13-IN-1 is utilized in research focused on cancer biology, particularly in exploring therapeutic strategies for tumors exhibiting CDK12/13 dependency.
CDK12/13-IN-1 is a selective inhibitor of cyclin-dependent kinases 12 and 13 (CDK12/13). This compound demonstrates significant antitumor activity by interfering with the phosphorylation of RNA polymerase II, thereby disrupting transcriptional regulation in cancer cells. CDK12/13-IN-1 is utilized in research focused on cancer biology, particularly in exploring therapeutic strategies for tumors exhibiting CDK12/13 dependency.
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