Fig. 1 · Structure
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CDK2/4-IN-2
CDK2/4 Inhibitor
CDK2/4-IN-2 is a potent dual inhibitor of cyclin-dependent kinases 2 and 4, exhibiting IC50 values below 100 nM. This compound is instrumental in cancer research, providing insights into cell cycle regulation and the therapeutic potential of targeting CDK pathways. Its efficacy in inhibiting CDK2 and CDK4 makes it a valuable reagent for investigating tumor cell proliferation and developing anti-cancer strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 3034898-59-1 |
| Applications | CDK2/4 Inhibitor |
| Formula | C18H20F3N7O3S2 |
| Molecular Weight | 503.52 |
| SMILES | O=S(C1=CNN=C1)(N2CCC(CC2)NC3=NC(C4=NC=C(C(C)O)S4)=C(C(F)(F)F)C=N3)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.