Fig. 1 · Structure

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CDK2/4 ligand 1

Ligand For Target Protein For PROTACs

CDK2/4 Ligand 1 is a specific ligand targeting cyclin-dependent kinases CDK2 and CDK4, designed for use in the development of proteolysis-targeting chimeras (PROTACs). It facilitates the synthesis of PROTAC CDK2/4 Degrader-1, enabling targeted degradation of these kinases to explore their role in various biological processes and cancers. This compound is essential for research applications focused on targeted protein degradation mechanisms.

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Specifications

Manufacturer Adooq Bioscience
Actions Ligand / Binder
CAS Number 1211585-07-7
Applications Ligand For Target Protein For PROTACs
Formula C5H5F2N3O
Molecular Weight 161.11
SMILES
NC1=NC=C(OC(F)F)C=N1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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