Fig. 1 · Structure
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CDK2 degrader 4
CDK2 Degrader
CDK2 Degrader 4 is a selective degrader that targets cyclin-dependent kinase 2 (CDK2). This compound promotes the degradation of CDK2, thereby inhibiting its activity in cell cycle regulation. CDK2 Degrader 4 is significant for cancer research, providing insights into CDK2's role in tumor growth and proliferation. Its application can aid in the development of targeted therapies for CDK2-dependent malignancies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Degrader |
| CAS Number | 2924122-01-8 |
| Applications | CDK2 Degrader |
| Formula | C23H26ClN3O5 |
| Molecular Weight | 459.92 |
| SMILES | O=C(NCC1=CC(Cl)=C2C(C(N(C3C(NC(CC3)=O)=O)C2)=O)=C1)OCC4CC5(C4)CCC5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.