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CDK2-IN-27

CDK2 Inhibitor

CDK2-IN-27 is a selective inhibitor of cyclin-dependent kinase 2 (CDK2), demonstrating potent inhibition with IC50 values of less than 10 nM for the CDK2/cyclin E1 complex and 10-20 nM for the CDK2/cyclin B1 complex. This compound is crucial for studies focused on cell cycle regulation and cancer research, where CDK2 plays a significant role in cell proliferation. CDK2-IN-27 provides valuable insights into therapeutic strategies targeting CDK2 to halt tumor growth and enhance cancer treatment regimens.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2927473-94-5
Applications	CDK2 Inhibitor
Formula	C₁₈H₂₁N₇O₂
Molecular Weight	367.41
SMILES	CC1(CC1)NC(O[C@H](CC2)C[C@H]2C3=CC(NC4=NC=C(C#N)N=C4)=NN3)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.