Fig. 1 · Structure
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CDK2-IN-40
CDK2 (Cyclin dependent kinase 2) Inhibitor
CDK2-IN-40 is a potent inhibitor of Cyclin-dependent kinase 2 (CDK2), demonstrating effective inhibition of the CDK2/Cyclin E1 complex with an IC50 value of ≤ 10 nM. This compound plays a significant role in regulating cell cycle progression and is valuable for research applications related to cancer therapy and cellular proliferation studies. CDK2-IN-40 can be utilized to explore the implications of CDK2 inhibition in various biological contexts.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 3065079-44-6 |
| Applications | CDK2 (Cyclin dependent kinase 2) Inhibitor |
| Formula | C16H21N7O2 |
| Molecular Weight | 343.38 |
| SMILES | CC(C)OC1=C(N=CN2C1=NC(NC3CCOCC3)=N2)C4=CNN=C4 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.