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CDK2-IN-52

CDK2 Inhibitor

CDK2-IN-52 is a selective inhibitor of cyclin-dependent kinase 2 (CDK2), exhibiting an impressive DC50 value of 1-10 nM. This compound effectively induces cell cycle arrest and inhibits the proliferation of tumor cells, making it a valuable tool for studying CDK2-overexpressing malignancies such as breast and ovarian cancers. CDK2-IN-52 facilitates research into potential therapeutic strategies targeting CDK2 in cancer treatment.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3038638-82-0
Applications	CDK2 Inhibitor
Formula	C₃₈H₄₇ClN₁₀O₄S
Molecular Weight	775.36
SMILES	O=C1NC(CCN1C2=NN(C)C3=C2C=CC(C4CCN(CC5CCN(CC5)C6=CC=CC(S(=O)(N7CCC(CC7)NC8=NC=C(C=N8)Cl)=O)=C6)CC4)=C3)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.