CDK4/6-IN-14 is a potent and highly selective inhibitor of cyclin-dependent kinases 4 and 6 (CDK4/6), displaying IC50 values of 10 nM and 16 nM, respectively. This compound exhibits over 60-fold selectivity compared to CDK1, CDK2, CDK7, and CDK9, while demonstrating high specificity against a broader panel of 205 kinases. CDK4/6-IN-14 is valuable for research into cell cycle regulation and has potential applications in studying cancer therapeutics and targeted therapies.
CDK4/6-IN-14 is a potent and highly selective inhibitor of cyclin-dependent kinases 4 and 6 (CDK4/6), displaying IC50 values of 10 nM and 16 nM, respectively. This compound exhibits over 60-fold selectivity compared to CDK1, CDK2, CDK7, and CDK9, while demonstrating high specificity against a broader panel of 205 kinases. CDK4/6-IN-14 is valuable for research into cell cycle regulation and has potential applications in studying cancer therapeutics and targeted therapies.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
