Fig. 1 · Structure

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CDK4/6-IN-24

CDK4/6 Inhibitor

CDK4/6-IN-24 is a potent inhibitor of cyclin-dependent kinases 4 and 6 (CDK4/6), key regulators of the cell cycle. This compound demonstrates broad-spectrum antitumor activity across various cancer cell lines, with IC50 values in the submicromolar range. CDK4/6-IN-24 is a valuable tool for researchers investigating cell cycle regulation and therapeutic strategies for cancer treatment.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 2662813-96-7
Applications CDK4/6 Inhibitor
Formula C32H41N7O3
Molecular Weight 571.71
SMILES
O=C1N(C2CCCC2)C3=NC(NC4=CC=C(N5[C@](CN(C6CCN(CC6)C)CC5)([H])CO7)C7=C4)=NC=C3C(C)=C1C(C)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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