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CDK4/9-IN-1

CDK4/9 Inhibitor

CDK4/9-IN-1 is a selective dual inhibitor of cyclin-dependent kinases 4 and 9, exhibiting IC50 values of 23 nM for CDK4 and 12 nM for CDK9. This compound demonstrates significant potential in the study of cancer biology, particularly in elucidating the role of CDK4 and CDK9 in the cell cycle and transcription regulation. Researchers may utilize CDK4/9-IN-1 to investigate therapeutic strategies targeting these kinases in various cancer models.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2577288-83-4
Applications	CDK4/9 Inhibitor
Formula	C₂₂H₃₄N₆O₂
Molecular Weight	414.54
SMILES	CN(C)C(C(N(C1CCCC1)C2=N3)=CC2=CN=C3N[C@@H]4CC[C@H](CC4)NCCO)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.